About Me

 

I will be starting as an Assistant Professor and Chancellor's Scholar in the Center for Emerging and Re-Emerging Pathogens and Department of Microbiology, Biochemistry and Molecular Genetics at Rutgers New Jersey Medical School on December 1, 2019. Please visit our new lab website: http://www.jasonyanglab.org/.

I am a Research Scientist in the Institute for Medical Engineering and Science at the Massachusetts Institute of Technology and in the Infectious Disease and Microbiome Program at the Broad Institute of MIT and Harvard. Since 2012, I have been collaborating with Dr. James Collins towards better understanding how antibiotics kill bacteria.

 

My overall research interests are to advance the practice of precision medicine and the mechanistic basis of cardiac and infectious diseases by engineering systems approaches combining network modeling and machine learning with experimental activities. Such approaches have the potential to reveal molecular mechanisms of disease pathogenesis and drug efficacy. I was awarded a NIH K99/R00 Career Development Award entitled "Effects of Host Metabolic Variation on Antibiotic Susceptibility" to pursue this work.

 

I received my Ph.D. from the University of Virginia in 2012 in Biomedical Engineering, under the guidance of Dr. Jeffrey Saucerman. In my dissertation, entitled "Systems Analysis of Cardiac β-Adrenergic Signaling Regulation", I investigated the roles of network topology and subcellular compartmentation in regulating selection of β-adrenergic signaling stimulated behaviors in cardiac myocytes.

 

I received my B.S. from Johns Hopkins University in 2005 with a double major in Biomedical Engineering and Electrical Engineering. There, I worked with Dr. Raimond Winslow on developing electrophysiological models of cardiac myocytes and with Dr. Robert Allen and Dr. Edith Gurewitsch on developing models of human childbirth.

 

My hobbies include rugby, hiking and riding my motorcycle.